科研成果
胃结肠外科2018年科研成果
更新时间:2019/6/12 23:10:28

获省级项目2项:

浙江省卫生和计划生育委员会省部共建重大项目,基于离体肿瘤组织三维培养的胃癌个体精准治疗研究,经费50万,沈贤

浙江省科协院士行业科技战略咨询项目,胃癌早期筛查新模式的建设及推广,经费30万,沈贤

省医药卫生科技项目,2019KY461,核定位的UBR5促结直癌细胞PYK2表达调控的机制研究,经费3万,黄颖鹏

省医药卫生学科平台项目,自噬相关通路Bif-1/mTOR/autophagy在肝癌细胞对Romidepsin产生耐药的机制研究,2018KY532,孙维健

院内课题:

其中护理3项:(黄书彬、陈新新、施孟花3项,经费自筹)。

 

合计经费约XXXX万。

2、论文:

发表SCI论文11篇,其中最高影响因子为23.259。

姓名

论文题目

影响因子

沈贤

Efficacy of PD-1 or PD-L1 inhibitors and PD-L1 expression status in cancer: meta-analysis

23.259

沈贤

Cyclic cRGDfk peptide and Chlorin e6 functionalized silk fibroin nanoparticles for targeted drug delivery and photodynamic therapy

8.806

沈贤

Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer

6.491

毛晨晨沈贤

A Novel Nomogram for Predicting Postsurgical Intra-abdominal Infection in Gastric Cancer Patients: a Prospective Study

2.813

沈贤

Sarcopenic Obesity Is Associated with Severe Postoperative Complications in Gastric Cancer Patients Undergoing Gastrectomy: a Prospective Study

2.813

纪伟平

沈贤

Enhanced recovery after surgery decreases intestinal recovery time and pain intensity in patients undergoing curative gastrectomy

3.702

沈贤

Investigating Potential Molecular Mechanisms of Carcinogenesis and Genes as Biomarkers for Prognosis of Gastric Cancer Based on Integrated Bioinformatics Analysis

1.935

卢明东

miR-135b-5p promotes gastric cancer progression by targeting CMTM3

3.333

俞耀军

The silencing of replication protein A1 induced cell apoptosis via regulating Caspase 3

3.234

徐晓武

SP1 reduces autophagic flux through activating p62 in gastric cancer cells.

1.922

李利义

Effect of Activated Carbon on Methomyl Poisoning by Urine Metabolomics Base on Gas Chromatography-Mass Spectrometry

0.773

3、专利:

纪伟平,专利3项,“无影灯把手保护套”、“一种引流管”、“一种用于微创手术的缝合装置”,实用新型专利;

孙维建,专利1项,“   一种肛瘘探针”,实用新型专利。


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